Review





Similar Products

kit reagent rk 03528  (ABclonal Biotechnology)
90
ABclonal Biotechnology kit reagent rk 03528
Kit Reagent Rk 03528, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/kit reagent rk 03528/product/ABclonal Biotechnology
Average 90 stars, based on 1 article reviews
kit reagent rk 03528 - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier
small molecule ssaa09e2 glxc-03528  (Glixx Laboratories Inc)
90
Glixx Laboratories Inc small molecule ssaa09e2 glxc-03528
Assessing a small molecule <t>(SSAA09E2)</t> as an inhibitor of the S1-ACE2 interaction. In each binding curve, the signals were normalized to the signal at 0 µM of inhibitor, which was set as 100% Response. ( a ) A binding curve of S1-ACE2 interaction with increasing concentrations of DMSO. The experiment was repeated three times ( n = 3 ) . ( b ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 in a final concentration of 1% v/v DMSO. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor and without DMSO. Error bars represent the standard error of the mean value of four experiments ( n = 4 ) . Four asterisks (****) indicate a statistical significance of p < 0.0001 . ( c ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 Maleate dissolved in DDW. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the average signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor. Error bars represent the standard error of the mean value of five experiments ( n = 5 ) . Three asterisks (***) indicate a statistical significance of p < 0.001 .
Small Molecule Ssaa09e2 Glxc 03528, supplied by Glixx Laboratories Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/small molecule ssaa09e2 glxc-03528/product/Glixx Laboratories Inc
Average 90 stars, based on 1 article reviews
small molecule ssaa09e2 glxc-03528 - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


Assessing a small molecule (SSAA09E2) as an inhibitor of the S1-ACE2 interaction. In each binding curve, the signals were normalized to the signal at 0 µM of inhibitor, which was set as 100% Response. ( a ) A binding curve of S1-ACE2 interaction with increasing concentrations of DMSO. The experiment was repeated three times ( n = 3 ) . ( b ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 in a final concentration of 1% v/v DMSO. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor and without DMSO. Error bars represent the standard error of the mean value of four experiments ( n = 4 ) . Four asterisks (****) indicate a statistical significance of p < 0.0001 . ( c ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 Maleate dissolved in DDW. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the average signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor. Error bars represent the standard error of the mean value of five experiments ( n = 5 ) . Three asterisks (***) indicate a statistical significance of p < 0.001 .

Journal: Sensors (Basel, Switzerland)

Article Title: Rapid and Sensitive Inhibitor Screening Using Magnetically Modulated Biosensors

doi: 10.3390/s21144814

Figure Lengend Snippet: Assessing a small molecule (SSAA09E2) as an inhibitor of the S1-ACE2 interaction. In each binding curve, the signals were normalized to the signal at 0 µM of inhibitor, which was set as 100% Response. ( a ) A binding curve of S1-ACE2 interaction with increasing concentrations of DMSO. The experiment was repeated three times ( n = 3 ) . ( b ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 in a final concentration of 1% v/v DMSO. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor and without DMSO. Error bars represent the standard error of the mean value of four experiments ( n = 4 ) . Four asterisks (****) indicate a statistical significance of p < 0.0001 . ( c ) A binding curve of S1-ACE2 interaction with increasing concentrations of SSAA09E2 Maleate dissolved in DDW. The experiment was repeated three times ( n = 3 ). (Inset) Abbreviations: “No inhibitor”, conjugated magnetic beads with the attached S1 protein were incubated with biotinylated ACE2 protein and SA-PE. “No ACE2”, conjugated magnetic beads with the attached S1 protein were incubated with the inhibitor and SA-PE, but without the ACE2 protein. Measurements were normalized to the average signal (designated as 100% Response) when S1 binds with ACE2 without an inhibitor. Error bars represent the standard error of the mean value of five experiments ( n = 5 ) . Three asterisks (***) indicate a statistical significance of p < 0.001 .

Article Snippet: According to the manufacturer’s recommendation, the small molecule SSAA09E2 (GLXC-03528, Glixx Laboratories Inc., Hopkinton, MA, USA) is dissolved in dimethyl sulfoxide (DMSO) at a concentration of 3 mg/mL, which is less than its reported solubility (~8 mg/mL).

Techniques: Binding Assay, Concentration Assay, Magnetic Beads, Incubation